Single-cell profiling of human bone marrow reveals multiple myeloma progression is accompanied by an increase in CD56bright bone marrow resident NK cells.
Elise Rees, Isabella Sodi, Kane A. Foster, Louise Ainley, Emma J. Lyon, Daria Galas‐Filipowicz, Jasmin Rahman, Rebekah Allen, Jessica Kimber, Aditya Prabu, Gwennan Ward, Dylan Jankovic, Annabel Laidler, Bethan Hudson-Lund, Selina J Chavda, , Kwee Yong
The paper shows that multiple myeloma progression is linked to increased CD56bright bone marrow resident NK cells, which may contribute to immune evasion.
bioRxiv · Feb 26, 2025 · PreprintCancer Biology