Cancer BiologybioRxivPreprint
Sequential acquisition of 1p31.1-p12 LOH and 1q Gain is a common double-hit event in relapsed/refractory myeloma
Naser Ansari‐Pour, Sarah Gooding, Mohammad H. Kazeroun…·Anjan Thakurta
The paper identifies a therapy-driven genomic double-hit (1pCEN LOH and 1q gain) in relapsed/refractory myeloma, associated with poor prognosis and clonal expansion.
DOI 10.64898/2026.05.19.726252