The haplolethal gene wupA of Drosophila exhibits potential as a target for an X-poisoning gene drive
Clancy Lawler, Ana Karla Parra Nuñez, Natalia Hernandes, Soumitra Bhide, Isabelle Lohrey, Simon W. Baxter, Charles Robin
The paper investigates a gene drive targeting the wupA gene in Drosophila to skew sex ratios, finding it can reduce female progeny and is effective across multiple species.
G3 Genes Genomes Genetics · Feb 2, 2024Peer-reviewedGenetics