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ISARIC-4C Investigators

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Biology Disciplines

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Microbiology· 1

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Darby· 1 shared C. Nelson· 1 shared COG-UK Consortium· 1 shared D. A. Matthews· 1 shared E. Vamos· 1 shared H. Goldswain· 1 shared J. A. Hiscox· 1 shared J. K. Baillie· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

A. Darby

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1 paper

Recent·Most cited

Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and dysregulation at later time points that can also be identified in humans

R. Penrice-Randal, H. Goldswain, T. Prince, N. Randle, J. Salguero, J. Tree, E. Vamos, C. Nelson, J. P. Stewart, ISARIC-4C Investigators, COG-UK Consortium, M. G. Semple, J. K. Baillie, P. J. M. Openshaw, L. Turtle, , J. A. Hiscox

The paper identifies and quantifies SARS-CoV-2 leader-TRS-junctions in samples, showing phasic sgmRNA transcription in animal models and dysregulation in humans.

bioRxiv · Mar 3, 2021Microbiology