The C. elegans nervous system reads the internal state of the hydrogen peroxide-detoxification machinery to trigger escape from this common reactive chemical
Yan Xu, Sahana Gangadharan, Maedeh Seyedolmohadesin, Eyob Gebeyaw, Alyson Fulton, Christopher Dante Ashih, Meagan Duncan, Matea J. Zelich, Jun Liu, Mahdi Torkashvand, Daniel Shaw, Katerina Gusarova, Meha Macwan, Avery Kelly, Isidora Beslic, , Javier Apfeld
The paper identifies a neural circuit in C. elegans that detects hydrogen peroxide and triggers escape by monitoring changes in the peroxiredoxin detoxification system.
bioRxiv · Jan 24, 2026 · PreprintNeuroscience