Antibiotic-induced Recombination in Escherichia coli Requires the Formation of DNA Double-Strand Breaks
Arpita Nath, Dan Roizman, Israa Amin, Nivetha Pachaimuthu, Jesús Blázquez, Olga Makarova, Jens Rolff, Alexandro Rodríguez-Rojas
This study shows that fluoroquinolones increase recombination in E. coli by causing DNA double-strand breaks, unlike other antibiotics that do not affect recombination.
bioRxiv · Mar 8, 2022 · PreprintMolecular Biology