Jesús Blázquez

This study investigates the role of NucS-mediated non-canonical mismatch repair in Mycobacterium tuberculosis and finds it does not significantly affect resistance to key antibiotics.

This study identifies the regulation of nucS expression in mycobacteria, showing growth phase-dependent downregulation and SigB-mediated repression, with implications for antibiotic resistance and stress adaptation.

This study investigates selamectin resistance in Mycobacterium smegmatis and finds that resistance requires specific mutations and intact cell envelope integrity.

This study shows that fluoroquinolones increase recombination in E. coli by causing DNA double-strand breaks, unlike other antibiotics that do not affect recombination.

This study shows that N-acetylcysteine reduces ROS and SOS response induced by ciprofloxacin, decreasing mutagenesis and suggesting a major role for ROS in antibiotic-induced mutagenesis.