Author

Israa Sharkia

Hebrew University of Jerusalem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Nir FriedmaniD· 2 shared Albert GrinshpuniD· 1 shared Alon ChappleboimiD· 1 shared Ami Ben YaʼacoviD· 1 shared Aviad ZickiD· 1 shared Ayala Hubert· 1 shared Ayelet Rahat· 1 shared Azzam Salah· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Nir FriedmanORCID

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2 papers

Recent·Most cited

Urine cf-Nucleosomes: A Non-invasive Window into Human Physiology and Disease

Matan Lotem, Israa Sharkia, Batia Azria, Esther Harpenas, Maayan Ormianer, Hadar Rosen, Tal Falick Michaeli, Nir Friedman

The paper demonstrates that urine contains cell-free nucleosomes that retain histone modifications and can reflect tissue-specific and pathological changes.

Cell Genomics · Aug 15, 2025Peer-reviewedGenomics

ChIP-seq of plasma cell-free nucleosomes identifies cell-of-origin gene expression programs

Ronen Sadeh, Israa Sharkia, Gavriel Fialkoff, Ayelet Rahat, Jenia Gutin, Alon Chappleboim, Mor Nitzan, Ilana Fox-Fisher, Daniel Neiman, Guy Meler, Zahala Kamari, Dayana Yaish, Tamar Peretz, Ayala Hubert, Jonathan E. Cohen, , Nir Friedman

The paper introduces cfChIP-seq to analyze cell-free nucleosomes and shows it can detect disease-related transcriptional changes and patient-specific features in cancer.

Nature Biotechnology · Jan 11, 2021Peer-reviewedMolecular Biology