Estrogen receptor alpha controls gene expression via translational offsetting
Julie Lorent, Eric P. Kusnadi, Vincent van Hoef, Richard J. Rebello, Matthew Leibovitch, Johannes Ristau, Shan Chen, Mitchell G. Lawrence, Krzysztof J. Szkop, Baila Samreen, Preetika Balanathan, Francesca A. Rapino, Pierre Close, Patricia E. Bukczynska, Karin Scharmann, , Luc Furic
This study shows estrogen receptor alpha (ER) regulates gene expression by coordinating transcription with translational offsetting, maintaining protein levels despite changes in mRNA abundance.
The EMBO Journal · Sep 26, 2019Peer-reviewedSystems Biology