J. A. Ayariga

Understanding the Mechanisms of Salmonella Typhimurium resistance to Cannabidiol

This study investigates the mechanisms of Salmonella Typhimurium resistance to Cannabidiol by analyzing gene expression and cell surface molecule changes in resistant strains.

CBD resistant Salmonella strains are susceptible to Epsilon 34 phage tailspike protein

This study shows that E34 phage tailspike protein effectively kills CBD-resistant Salmonella strains, outperforming combined treatment with CBD.

Molecular docking studies of potential inhibitors of acyl carrier protein and acetyl CoA Carboxylase in Plasmodium falciparum.

This study identifies potential inhibitors of two enzymes in Plasmodium falciparum using in silico techniques, showing favorable binding and pharmacokinetic properties.

Proteolytic Analysis of Epsilon 34 Phage Tailspike protein indicates Partial Sensitivity to Proteinase K

The paper shows that {varepsilon}34 TSP is partially sensitive to proteinase K, unlike P22 TSP which is completely resistant, and identifies structural motifs responsible for this difference.

Capsaicin potently blocks Salmonella typhimurium invasion of Vero cells

This study tests capsaicin and its extract against Salmonella typhimurium, finding both inhibit bacterial growth and block invasion of Vero cells.

In silico Elucidation of Dihydroquinine Mechanism of Action against Toxoplasma gondii

This study identifies DHQ's potential targets in T. gondii through in silico analysis, suggesting it may inhibit DNA replication, transcription, translation, and mitochondrial detoxification.

Single Amino Acid Change Mutation in the Hydrophobic Core of the N-terminal Domain of P22 TSP affects the Proteins Stability.

The paper investigates how a single amino acid change in the hydrophobic core of the P22 TSP N-terminal domain affects protein stability through computational and in vitro assays.

The E34 Phage Tailspike Protein: An in vitro characterization, Structure Prediction, Potential Interaction with S. newington LPS and Cytotoxicity Assessment to Animal Cell Line.

This study characterizes the E34 phage tailspike protein, identifies key residues for LPS binding and hydrolysis, and shows its potential as a therapeutic against Salmonella infection.