Author

J. A. Brazzo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Y. Bae· 3 shared K. Lee· 2 shared A. Krajnik· 1 shared A. Sullivan· 1 shared I. Dang· 1 shared J. C. Biber· 1 shared J. Kolega· 1 shared K. E. Poppenberg· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

Y. Bae

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Author profile →

3 papers

Recent·Most cited

Survivin is a mechanosensitive cell cycle regulator in vascular smooth muscle cells

J. C. Biber, A. Sullivan, J. A. Brazzo, A. Krajnik, Y. Heo, K. E. Poppenberg, V. M. Tutino, S.-J. Heo, J. Kolega, K. Lee, Y. Bae

The paper identifies survivin as a mechanosensitive regulator of cell cycle progression in vascular smooth muscle cells under mechanical stress.

bioRxiv · Nov 9, 2022 · PreprintCell Biology

Rac rather than Rho drives the early transcriptional response to extracellular matrix stiffness and mediates repression of ATF3

I. Dang, Y. Bae, J. A. Brazzo, R. K. Assoian

The paper investigates the role of Rac and Rho in the transcriptional response to ECM stiffness and finds Rac drives the early response and represses ATF3.

bioRxiv · Apr 27, 2022 · PreprintCell Biology

Mechanosensitive Expression of Lamellipodin Governs Cell Cycle Progression and Intracellular Stiffness

J. A. Brazzo, K. Lee, Y. Bae

This study shows that ECM stiffness increases lamellipodin expression, which drives cell cycle progression and intracellular stiffness throughout the cell cycle.

bioRxiv · Oct 30, 2020 · PreprintCell Biology