Shift from a Simplified to Complex Gut Microbiota Reduces Adenoma Burden in a Preclinical Rat Model of Colon Cancer
S. B. Busi, D. Davis, J. Moskowitz, J. Amos-Landgraf
bioRxiv · Jan 20, 2023 · PreprintMicrobiology
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S. B. Busi, D. Davis, J. Moskowitz, J. Amos-Landgraf
bioRxiv · Jan 20, 2023 · PreprintMicrobiology
S. B. Busi, K. B. De Leon, D. R. Montonye, J. D. Wall, J. Amos-Landgraf
This study shows that biofilm-forming Desulfovibrio vulgaris Hildenborough colonizes rat colons and reduces adenoma development, while biofilm-deficient strains do not persist and increase mucin expression.
bioRxiv · Jul 26, 2022 · PreprintMicrobiology
S. B. Busi, Z. Lei, L. Sumner, J. Amos-Landgraf
The paper uses multi-omics analyses to show how gut microbiota influence metabolome and transcriptome changes linked to colon cancer susceptibility in rats.
bioRxiv · Jul 24, 2020 · PreprintCancer Biology