Structural anatomy of C1 domain interactions with DAG and other agonists
S. S. Katti, I. V. Krieger, J. Ann, J. Lee, J. C. Sacchettini, T. I. Igumenova
The paper reports high-resolution crystal structures of a C1 domain bound to DAG and agonists, revealing mechanisms of lipid recognition and guiding drug design.
bioRxiv · Sep 3, 2021 · PreprintBiophysics