Author

J. Astren

Turku University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandra LahtineniD· 1 shared Anni VirtaneniD· 1 shared Antti HäkkineniD· 1 shared Chiara FacciottoiD· 1 shared Daria AfentevaiD· 1 shared Elina ValkoneniD· 1 shared Elsi Pöllänen· 1 shared Felix DietleiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alexandra LahtinenORCID

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1 paper

Recent·Most cited

Spatio-Temporal Landscape of Whole-Genome DNA Methylation Patterns in Ovarian Cancer

Giovanni Marchi, Kari Lavikka, Yilin Li, Veli‐Matti Isoviita, Giulia Micoli, Daria Afenteva, Elsi Pöllänen, Susanna Holmström, Antti Häkkinen, Elina Valkonen, Ilari Maarala, J. Astren, Chiara Facciotto, Felix Dietlein, Sakari Hietanen, , Sampsa Hautaniemi

This study maps the spatio-temporal DNA methylation patterns in ovarian cancer using longitudinal data from the DECIDER trial, showing early establishment of regulatory methylomes and their stability through treatment.

medRxiv · Mar 25, 2026 · PreprintGenetic & Genomic Medicine