A Vibrio cholerae Type IV restriction system targets glucosylated 5-hydroxyl methyl cytosine to protect against phage infection
This study identifies a novel Type IV restriction system in V. cholerae, TgvAB, that targets glucosylated 5-hydroxymethylcytosine on phage DNA, revealing evolutionary tradeoffs in phage resistance.
bioRxiv · Apr 5, 2024 · PreprintMicrobiology