Author

K. J. Card

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5

Signature Assays, Organisms & Methods

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Organism:E. coli· 4 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

R. E. Lenski· 4 shared J. A. Jordan· 2 shared A. Durmaz· 1 shared A. Stocks· 1 shared D. Crozier· 1 shared J. A. Maltas· 1 shared J. B. Gomez· 1 shared J. Creary· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersEvolutionary Biology

R. E. Lenski

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5 papers

Recent·Most cited

Evolution under vancomycin selection drives divergent collateral sensitivity patterns in Staphylococcus aureus

K. J. Card, D. Crozier, A. Durmaz, J. M. Gray, J. Creary, A. Stocks, J. A. Maltas, R. A. Bonomo, Z. D. C. Burke, J. G. Scott

This study evolves Staphylococcus aureus under vancomycin selection, revealing two distinct adaptive pathways that lead to divergent collateral sensitivity patterns to first-line antibiotics.

bioRxiv · Nov 30, 2023Evolutionary Biology

Idiosyncratic fitness costs of ampicillin-resistant mutants derived from a long-term experiment with Escherichia coli

J. A. Jordan, R. E. Lenski, K. J. Card

The paper examines the fitness costs of ampicillin-resistant mutants derived from Escherichia coli, finding significant variation in fitness costs not linked to resistance levels or parental backgrounds.

bioRxiv · Feb 6, 2022Evolutionary Biology

Idiosyncratic variation in the fitness costs of tetracycline-resistance mutations in Escherichia coli

K. J. Card, J. A. Jordan, R. E. Lenski

The study shows that tetracycline-resistant Escherichia coli mutants have variable fitness costs, independent of resistance level or genetic background.

bioRxiv · Sep 12, 2020Evolutionary Biology

Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli

K. J. Card, M. D. Thomas, J. L. Graves, J. E. Barrick, R. E. Lenski

This study shows that genetic background influences the genotypic evolution of antibiotic resistance in Escherichia coli, leading to divergent mutational paths despite similar antibiotic treatments.

bioRxiv · Aug 19, 2020Evolutionary Biology

Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection

K. J. Card, T. LaBar, J. B. Gomez, R. E. Lenski

This study shows that relaxed antibiotic selection in E. coli leads to increased susceptibility and unpredictable evolvability of resistance when selection is restored.

bioRxiv · Jul 10, 2019Evolutionary Biology