Author

J. B. Reichelt

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Pharmacology & Toxicology· 1

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Organism:Drosophila· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Elkasaby· 1 shared A. Kasture· 1 shared C. Pifl· 1 shared D. Boytsov· 1 shared M. Freissmuth· 1 shared S. Bhat· 1 shared S. Sucic· 1 shared T. Hummel· 1 shared

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2022-2022 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Elkasaby

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1 paper

Recent·Most cited

A mechanism of uncompetitive inhibition of the serotonin transporter

S. Bhat, A. Elkasaby, A. Kasture, D. Boytsov, J. B. Reichelt, T. Hummel, S. Sucic, C. Pifl, M. Freissmuth, W. Sandtner

This paper identifies ECSI#6 as an uncompetitive inhibitor of the serotonin transporter, showing it preferentially binds to the K+-bound inward-facing conformation and acts as a pharmacochaperone for misfolded variants.

bioRxiv · Aug 11, 2022Pharmacology & Toxicology