Conserved Cdk inhibitors show unique structural responses to tyrosine phosphorylation
J. B. Swadling, T. Warnecke, K. L. Morris, A. R. Barr
The paper uses molecular dynamics simulations to compare structural changes in Cyclin/Cdk/CKI trimers due to tyrosine phosphorylation in CKIs and their impact on Cdk activity.
bioRxiv · Feb 4, 2021Cell Biology