WILMS TUMORIGENESIS IN HUMAN KIDNEY ORGANOIDS
V. Waehle, R. Ungricht, P. S. Hoppe, J. Betschinger
This study models Wilms tumor initiation in human kidney organoids by showing WT1 loss halts progenitor cell differentiation and recapitulates tumor-like transcriptional changes.
bioRxiv · Feb 2, 2021Cancer Biology