J. C. Fay

Divergence in the Saccharomyces species' heat shock response is indicative of their thermal tolerance

The study compares heat shock responses across Saccharomyces species and hybrids to assess thermal tolerance divergence.

Fluctuating selection facilitates the discovery of broadly effective but difficult to reach adaptive outcomes in yeast

This study shows fluctuating selection in yeast can lead to the evolution of broadly effective, no-cost generalists that outperform specialists in their own environments.

Using colony size to measure fitness in Saccharomyces cerevisiae

This study shows colony size can measure fitness in yeast as effectively as liquid culture assays, after accounting for edge effects.

Macroevolutionary diversity of traits and genomes in the model yeast genus Saccharomyces

The paper studies genetic and phenotypic diversity across 1,800 Saccharomyces strains, revealing insights into macroevolutionary processes and gene flow effects on traits.

Cis-regulatory variants affect gene expression dynamics in yeast

The paper identifies cis-regulatory variants in yeast that influence gene expression dynamics during the diauxic shift, showing that insertions and deletions have a stronger effect than ASE levels.

The structure and diversity of strain level variation in vaginal bacteria

The paper measures strain-level variation in vaginal bacteria using metagenomic data and finds that strain diversity and structure vary across species, with lower diversity in Lactobacillus species.

High-throughput analysis of adaptation using barcoded strains of Saccharomyces cerevisiae

This paper develops a high-throughput experimental evolution system in yeast using genetic barcoding to measure fitness and adaptation across multiple populations and conditions.

Multiple changes underlie allelic divergence of CUP2 between Saccharomyces species.

The paper identifies multiple nucleotide changes in the CUP2 gene contributing to copper resistance divergence between Saccharomyces species.

Mitochondria-encoded genes contribute to the evolution of heat and cold tolerance among Saccharomyces species

The paper identifies mitochondrial DNA contributions to thermal tolerance differences between Saccharomyces species through genetic screening and recombinant analysis.