Hierarchical and scaffolded phosphorylation of two degrons controls PER2 stability
J. C. Francisco, D. M. Virshup
This study investigates how two degrons in PER2 regulate its stability through phosphorylation by CK1, revealing that D1 acts as a backup degron and enables scaffolded phosphorylation in PER1:PER2 dimers.
bioRxiv · Nov 2, 2023Cell Biology