Fractal dimension, occupancy and hotspot analyses of B cell spatial distribution predict clinical outcome in breast cancer
J. C. Wortman, T.-F. He, S. Solomon, R. Z. Zhang, A. Rosario, R. Wang, T. Y. Tu, D. Schmolze, Y. Yuan, S. E. Yost, X. Li, H. Levine, G. Atwal, P. P. Lee, C. C. Yu
The paper analyzes the spatial distribution of B cells in breast cancer tumors using novel statistical methods and finds that their spatial arrangement correlates with clinical outcomes.
bioRxiv · Jun 21, 2019 · PreprintCancer Biology