Author

S. E. Yost

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Y. Yuan· 2 shared A. Rosario· 1 shared A. S. Zhu· 1 shared C. C. Yu· 1 shared D. Schmolze· 1 shared E. M. Swisher· 1 shared E. T. Liu· 1 shared F. Menghi· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Y. Yuan

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2 papers

Recent·Most cited

Specific BRCA and immune configurations determine optimal response to platinum-based chemotherapy in triple negative breast and ovarian carcinomas

F. Menghi, K. Banda, P. Kumar, R. Straub, L. Dobrolecki, I. V. Rodriguez, S. E. Yost, H. Chandok, M. R. Radke, A. S. Zhu, G. Somlo, Y. Yuan, M. T. Lewis, E. M. Swisher, E. T. Liu

This study identifies that BRCA1 promoter methylation (BRCA1meth) leads to adaptive recovery of BRCA1 expression and poorer response to platinum chemotherapy compared to BRCA mutations, while immune signals enhance response in BRCA-proficient cancers.

bioRxiv · Aug 19, 2021 · PreprintCancer Biology

Fractal dimension, occupancy and hotspot analyses of B cell spatial distribution predict clinical outcome in breast cancer

J. C. Wortman, T.-F. He, S. Solomon, R. Z. Zhang, A. Rosario, R. Wang, T. Y. Tu, D. Schmolze, Y. Yuan, S. E. Yost, X. Li, H. Levine, G. Atwal, P. P. Lee, C. C. Yu

The paper analyzes the spatial distribution of B cells in breast cancer tumors using novel statistical methods and finds that their spatial arrangement correlates with clinical outcomes.

bioRxiv · Jun 21, 2019 · PreprintCancer Biology