Author

J. Choza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

C. Ma· 2 shared J. Wang· 2 shared Y. Wang· 2 shared H. Tan· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

C. Ma

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2 papers

Recent·Most cited

Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays

C. Ma, H. Tan, J. Choza, Y. Wang, J. Wang

This study validates and invalidates SARS-CoV-2 main protease inhibitors using cell-based and cell-free assays, showing most repurposed drugs are not specific to Mpro.

Acta Pharmaceutica Sinica B · Apr 1, 2022Peer-reviewedBiochemistry

Drug repurposing screening identified tropifexor as a SARS-CoV-2 papain-like protease inhibitor

C. Ma, Y. Wang, J. Choza, J. Wang

This study identifies tropifexor as a potent SARS-CoV-2 PLpro inhibitor through drug repurposing screening, showing antiviral activity in Calu-3 cells.

bioRxiv · Dec 2, 2021Pharmacology & Toxicology