Oncogenic metabolic rewiring independent of proliferative control in human mammary epithelial cells
W. Dong, M. A. Keibler, S. J. Moon, P. Cho, N. Liu, C. J. Berrios, J. Kelleher, H. D. Sikes, O. Iliopoulos, J. Coloff, M. Vander Heiden, G. Stephanopoulos
The paper compares metabolic flux in cancerous and normal human mammary epithelial cells using 13C-tracing and MFA, finding distinct metabolic pathways activated in cancer cells.
bioRxiv · Apr 8, 2022 · PreprintBiochemistry