On the function of TRAP substrate-binding proteins: conformational variation of the sialic acid binding protein SiaP
T.-R. J. King-Hudson, J. S. Davies, S. Quan, M. Currie, Z. D. Tillett, J. Copping, S. Panjikar, R. Friemann, J. R. Allison, R. A. North, R. Dobson
This study solves the structure of the TRAP substrate-binding protein AaSiaP in different conformations, revealing how it binds N-acetylneuraminate and stabilizes a closed state.
bioRxiv · Apr 30, 2024Biochemistry