PARP1 and MGMT interaction-based sensitivity to DNA damage in Ewing sarcoma
D. Alimbetov, J. Cropper, R. Likhotvorik, R. Carlson, Y. Kwon, R. Kurmasheva
This study shows that PARP1 and MGMT interact and work epistatically to repair DNA damage in Ewing sarcoma, suggesting potential for improved DNA-damaging therapies.
bioRxiv · Jan 26, 2020Biochemistry