RAD51AP1 mediates RAD51 activity through nucleosome interaction
E. Pires, N. Sharma, P. Selemenakis, B. Wu, Y. Huang, D. Alimbetov, W. Zhao, C. Wiese
This study shows RAD51AP1 binds nucleosomes and aids RAD51 in chromatin-mediated DNA repair by facilitating donor DNA capture and joint-molecule formation.
bioRxiv · Dec 17, 2020Biochemistry