2.7 A cryo-EM structure of ex vivo RML prion fibrils
S. W. Manka, W. Zhang, A. Wenborn, J. Betts, S. Joiner, H. R. Saibil, J. Collinge, J. D. F. Wadsworth
The paper presents a cryo-EM structure of prion fibrils from RML prion-infected mice, revealing structural features and conformational variations that may influence prion strain diversity and propagation.
bioRxiv · Dec 13, 2021Biochemistry