Electron cryo-microscopy structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome.
J.-P. Armache, N. Gamarra, S. L. Johnson, J. D. Leonard, S. Wu, G. J. Narlikar, Y. Cheng
The paper presents cryo-EM structures of SNF2h-nucleosome complexes with ADP-BeFx, revealing conformational states that suggest allosteric control through the nucleosome.
bioRxiv · Feb 15, 2019Biophysics