Author

S. L. Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

A. Grierson· 1 shared A. Hanuka· 1 shared A. Heckert· 1 shared A. Klammer· 1 shared A. Odriozola· 1 shared A. P. Rose· 1 shared A. Sule· 1 shared A. Tsakiridis· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Grierson

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Author profile →

7 papers

Recent·Most cited

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

D. T. McSwiggen, H. Liu, R. Tan, S. Agramunt Puig, L. B. Akella, R. Berman, M. Bretan, H. Chen, X. Darzacq, K. Ford, R. Godbey, E. Gonzalez, A. Hanuka, A. Heckert, J. J. Ho, , H. Beck

This paper introduces a high-throughput single-molecule tracking platform to study protein dynamics and drug interactions, identifying novel mechanisms and therapeutics.

bioRxiv · Jan 5, 2023Cell Biology

HDAC6 inhibition partially alleviates mitochondrial trafficking defects and restores motor function in human motor neuron and zebrafish models of Charcot-Marie-Tooth Disease Type 2A

L. Butler, K. I. Adamson, S. L. Johnson, L. Jestice, C. J. Price, D. Stavish, N. Pooranachandran, A. Tsakiridis, A. Grierson, I. Barbaric

This study shows HDAC6 inhibition improves mitochondrial trafficking and motor function in CMT2A models using human motor neurons and zebrafish.

bioRxiv · Jul 5, 2022 · PreprintCell Biology

ATP hydrolysis coordinates the activities of two motors in a dimeric chromatin remodeling enzyme

S. L. Johnson, G. Narlikar

The paper studies how ATP hydrolysis coordinates two motors in a dimeric chromatin remodeler to slide a nucleosome directionally.

bioRxiv · Nov 17, 2020Biophysics

Cryptosporulation in Kurthia spp. forces a rethinking of asporogenesis in Firmicutes

S. Filippidou, M. Fatton, T. Junier, M. Berge, D. Poppleton, T. B. Blum, M. Kaminek, A. Odriozola, J. Blom, S. L. Johnson, J. P. Abrahams, P. S. G. Chain, S. Gribaldo, E. I. Tocheva, B. Zuber, , P. Junier

The paper demonstrates endosporulation in the genus Kurthia, previously considered asporogenic, and proposes a revised understanding of sporulation in Firmicutes.

bioRxiv · Jun 18, 2020 · PreprintMicrobiology

Environmental unpredictability shapes glucocorticoid regulation across populations of tree swallows

C. Zimmer, C. C. Taff, D. R. Ardia, A. P. Rose, D. A. Aborn, S. L. Johnson, M. N. Vitousek

This study examines how environmental unpredictability influences glucocorticoid regulation in tree swallow populations, finding stronger stress responses in unpredictable environments and a mitigating effect of negative feedback.

bioRxiv · Dec 23, 2019Evolutionary Biology

Electron cryo-microscopy structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome.

J.-P. Armache, N. Gamarra, S. L. Johnson, J. D. Leonard, S. Wu, G. J. Narlikar, Y. Cheng

The paper presents cryo-EM structures of SNF2h-nucleosome complexes with ADP-BeFx, revealing conformational states that suggest allosteric control through the nucleosome.

bioRxiv · Feb 15, 2019Biophysics

The evolution of a super-swarm of foot-and-mouth disease virus in cattle

J. Arzt, I. Fish, S. J. Pauszek, S. L. Johnson, P. S. Chain, D. K. Rai, E. Rieder, T. L. Goldberg, L. L. Rodriguez, C. Stenfeldt

This study tracks FMDV evolution in cattle, finding that viral haplotypes shift early in infection but stabilize later, with mutations and minority haplotype emergence driving diversity.

bioRxiv · Jan 4, 2019Microbiology