Author

J. D. Nguyen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 9 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Organism:rat· 8 Research Focus:host-pathogen & immune response· 7 Assay:behavioral assay· 6 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. A. Taffe· 9 shared K. M. Creehan· 6 shared Y. Grant· 6 shared A. Gutierrez· 5 shared T. M. Kerr· 4 shared S. A. Vandewater· 3 shared M. Javadi-Paydar· 2 shared A. Smith· 1 shared

Activity by Year

2018-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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9 shared papersPharmacology & Toxicology

M. A. Taffe

Mutual co-authors in cluster

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10 papers

Recent·Most cited

Oxycodone Self-Administration in Female Rats is Enhanced by Δ9-tetrahydrocannabinol, but not by Cannabidiol, in a Progressive Ratio Procedure

J. D. Nguyen, Y. Grant, C. Yang, A. Gutierrez, M. A. Taffe

This study shows THC enhances oxycodone self-administration in female rats under progressive ratio schedules, while CBD reduces it in fixed ratio schedules.

bioRxiv · Oct 26, 2023 · PreprintPharmacology & Toxicology

Adult consequences of repeated nicotine vapor inhalation in adolescent rats

A. Gutierrez, J. D. Nguyen, K. M. Creehan, Y. Grant, M. A. Taffe

This study examines the long-term behavioral effects of adolescent nicotine vapor exposure in rats, finding increased nicotine self-administration in females but minimal impact on locomotor activity.

bioRxiv · Nov 17, 2022Pharmacology & Toxicology

Vapor exposure to Δ9-tetrahydrocannabinol (THC) slows locomotion of the Maine Lobster (Homarus americanus)

A. Gutierrez, K. M. Creehan, M. L. Turner, R. N. Tran, T. M. Kerr, J. D. Nguyen, M. A. Taffe

This study exposes Maine lobsters to THC vapor and finds reduced locomotion but minimal effect on nociception.

bioRxiv · May 24, 2021Pharmacology & Toxicology

THC modifies the impact of heroin delivered by vapor inhalation in rats

A. Gutierrez, J. D. Nguyen, K. M. Creehan, M. Javadi-Paydar, Y. Grant, M. A. Taffe

This study investigates the interaction between heroin and THC in rats, finding additive effects on thermal nociception but opposing effects on temperature and activity.

bioRxiv · Apr 26, 2021 · PreprintPharmacology & Toxicology

Distinguishing the behavioral potencies of α-pyrrolidino-phenone cathinone stimulants

M. A. Taffe, J. D. Nguyen, S. A. Vandewater, Y. Grant, T. J. Dickerson

This study compares the behavioral effects of three cathinone stimulants in rats, finding similar stimulant activity with minor differences in potency and duration.

bioRxiv · Dec 14, 2020 · PreprintPharmacology & Toxicology

A small molecule screen identified N-Acetyl-L-cysteine for promoting ex vivo growth of single circulating tumor cells

T. Teng, M. Kamal, O. Iriondo, Y. Amzaleg, C. Luo, A. Thomas, G. Lee, J. D. Nguyen, A. Smith, R. Sposto, M. Yu

The paper identifies N-acetylcysteine (NAC) as a compound that promotes ex vivo growth of single circulating tumor cells by reducing oxidative stress.

bioRxiv · Aug 19, 2020 · PreprintCancer Biology

Explication of CB1 receptor contributions to the hypothermic effects of Δ9-tetrahydrocannabinol (THC) when delivered by vapor inhalation or parenteral injection in rats

J. D. Nguyen, K. M. Creehan, Y. Grant, S. A. Vandewater, T. M. Kerr, M. A. Taffe

This study investigates how CB1 receptor activation contributes to THC-induced hypothermia via inhalation or injection in rats, finding that CB1 antagonists only partially block or alter the hypothermic response.

bioRxiv · May 22, 2020Pharmacology & Toxicology

Female rats self-administer heroin by vapor inhalation

A. Gutierrez, J. D. Nguyen, K. M. Creehan, M. A. Taffe

This study shows that female rats self-administer heroin via e-cigarette vapor, producing anti-nociceptive effects similar to intravenous administration and inducing withdrawal-like anxiety.

bioRxiv · Mar 30, 2020Pharmacology & Toxicology

Lasting effects of repeated Δ9-tetrahydrocannabinol (THC) vapor inhalation during adolescence in male and female rats

J. D. Nguyen, K. M. Creehan, T. M. Kerr, M. A. Taffe

This study examines the lasting effects of repeated THC vapor inhalation during adolescence in rats, finding sex-specific changes in thermoregulation, food intake, and drug self-administration.

bioRxiv · Jul 24, 2019Pharmacology & Toxicology

Effects Of Δ9-THC And Cannabidiol Vapor Inhalation In Male And Female Rats

M. Javadi-Paydar, J. D. Nguyen, T. M. Kerr, Y. Grant, S. A. Vandewater, M. Cole, M. A. Taffe

This study compares thermoregulatory and locomotor responses to THC, CBD, and their combination inhaled via vapor in male and female rats, finding equivalent effects with subtle sex differences.

bioRxiv · Mar 7, 2018Pharmacology & Toxicology