In-cell detection of conformational sub-states of a GPCR quaternary structure: Modulation of sub-state probability by cognate ligand binding
J. D. Paprocki, G. Biener, M. R. Stoneman, V. Raicu
This study improves FRET spectrometry to detect conformational sub-states of GPCR oligomers and shows ligand binding modulates these sub-states in Ste2.
bioRxiv · Jun 29, 2020Biophysics