Author

J. D. Winkler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:protein design· 1 Approach:statistical model· 1

Frequent Co-Authors

A. D. Glass· 1 shared A. Pines· 1 shared C. Mesaros· 1 shared E. M. Behrens· 1 shared G. Pines· 1 shared I. de Jong· 1 shared J. Llewellyn· 1 shared J. P. Xu· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. D. Glass

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2 papers

Recent·Most cited

Biliatresone treatment of pregnant mice causes changes in bile metabolism and liver inflammation in their offspring

K. Gupta, J. P. Xu, T. Diamond, I. de Jong, A. D. Glass, J. Llewellyn, N. D. Theise, J. D. Winkler, E. M. Behrens, C. Mesaros, R. G. Wells

This study shows that prenatal exposure to low-dose biliatresone in mice leads to altered bile metabolism and liver inflammation in offspring without histological damage.

bioRxiv · Mar 2, 2023 · PreprintPharmacology & Toxicology

Refactoring the Genetic Code for Increased Evolvability

G. Pines, J. D. Winkler, A. Pines, R. T. Gill

This paper proposes alternative genetic codes that enhance evolvability by increasing the mutational accessibility of amino acids through single nucleotide replacements.

bioRxiv · Apr 17, 2017Bioengineering