Mathematical Modelling Indicates Th-cell Targeted Antibody-Dependent Cellular Cytotoxic Is a Crucial Obstacle Hurdling HIV Vaccine Development
Z. Xu, Q. Zeng, D. Yang, X. Sun, D. Wei, J. Demongeot, Z. Cao
This paper uses mathematical modeling to show that ADCC targeting Th cells hinders HIV vaccine development by damaging immune responses and reducing vaccine effectiveness.
bioRxiv · Feb 7, 2024 · PreprintImmunology