Hydrogen-deuterium exchange reveals a dynamic DNA binding map of Replication Protein A
F. Ahmed, A. Patterson, J. Devershetty, J. Mattice, N. Pokhrel, B. Bothner, E. Antony
This study uses HDX-MS to analyze the dynamic DNA binding properties of RPA domains, revealing that DBD-C is most involved in stabilizing RPA on ssDNA.
bioRxiv · Sep 4, 2020Biochemistry