Author

J. E. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Physiology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. M. Trumbull· 1 shared C. Kuo· 1 shared J. B. Sarthi· 1 shared J. Gammons· 1 shared M. O. Andrerson· 1 shared O. Cil· 1 shared S. M. Abazari· 1 shared V. van Unen· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

A. M. Trumbull

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1 paper

Recent·Most cited

Key role of down-regulated in adenoma (SLC26A3) chloride/bicarbonate exchanger in linaclotide-stimulated intestinal bicarbonate secretion upon loss of CFTR function

J. B. Sarthi, A. M. Trumbull, S. M. Abazari, V. van Unen, J. E. Chan, Y. Jiang, J. Gammons, M. O. Andrerson, O. Cil, C. Kuo, Z. M. Sellers

This study shows linaclotide stimulates bicarbonate secretion in CFTR-deficient tissues by enhancing DRA expression, suggesting DRA as a therapeutic target for CF-related intestinal dysfunction.

bioRxiv · May 5, 2023 · PreprintPhysiology