Author

J. E. Heggelund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:structural biology· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

U. Krengel· 2 shared A. Bernardi· 1 shared A. Mackenzie· 1 shared G. Anderluh· 1 shared J. B. Heim· 1 shared P. Cheshev· 1 shared T. Martinsen· 1 shared V. Hodnik· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

U. Krengel

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2 papers

Recent·Most cited

Crystal structures reveal that Lewis-x and fucose bind to secondary cholera toxin binding site - in contrast to fucosyl-GM1

J. B. Heim, V. Hodnik, J. E. Heggelund, G. Anderluh, U. Krengel

The paper reports crystal structures and SPR data showing Lewis-x and fucose bind to a secondary cholera toxin binding site, distinct from the GM1 binding site.

Scientific Reports · Aug 22, 2019Peer-reviewedBiochemistry

Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics

J. E. Heggelund, A. Mackenzie, T. Martinsen, P. Cheshev, A. Bernardi, U. Krengel

This paper presents crystal structures of bacterial enterotoxins complexed with GM1 mimics, revealing molecular interactions that could guide the design of new cholera prophylactics.

Scientific Reports · May 24, 2017Peer-reviewedBiochemistry