Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics in a high-cholesterol diet mouse model
J. E. Joll, C. Clark, C. Scott, M. Raddatz, M. Bersi, W. D. Merryman
This study shows genetic ablation of Htr2b reduces hemodynamic indicators of aortic valve stenosis in a mouse model of CAVD, but pharmacological antagonism had no effect.
bioRxiv · Aug 18, 2020Pharmacology & Toxicology