Author

J. E. Tavis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. G. Casals· 1 shared A. J. Berkowitz· 1 shared A. K. Pinto· 1 shared A. T. O'Dea· 1 shared B. E.-D. M. Elgendy· 1 shared D. P. Bradley· 1 shared D. V. Schiavone· 1 shared E. Geerling· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

A. G. Casals

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Metal Coordinating Inhibitors of Rift Valley Fever virus Replication

E. Geerling, V. Murphy, E. T. Stone, A. G. Casals, M. A. Hassert, A. T. O'Dea, F. Cao, M. J. Donlin, B. E.-D. M. Elgendy, M. Elagawany, V. Pardali, E. Giannakopoulou, G. Zoidis, D. V. Schiavone, A. J. Berkowitz, , J. D. D. Brien

This study identifies 31 novel RVFV replication inhibitors with selective indexes and effective concentrations, primarily -Hydroxytropolones and N-Hydroxypyridinediones, validated in human cells and tested against related Bunyaviruses.

bioRxiv · Mar 10, 2022Microbiology

Predicted structure of the hepatitis B virus polymerase reveals an ancient conserved protein fold

R. Tajwar, D. P. Bradley, N. L. Ponzar, J. E. Tavis

This paper predicts the structure of hepatitis B virus polymerase, revealing an ancient conserved fold that persists across hepadnaviruses and informs drug development.

bioRxiv · Feb 16, 2022Microbiology

Establishment of a Replicon System for Bourbon Virus and Identification of Small Molecules that Efficiently Inhibit Virus Replication

S. Hao, K. Ning, X. Wang, J. Wang, F. Cheng, S. S. Ganaie, J. E. Tavis, J. Qiu

This study establishes a BRBV replicon system and identifies myricetin as a potent inhibitor of BRBV replication with a high therapeutic index.

bioRxiv · Apr 24, 2020 · PreprintMicrobiology