Author

J. E. Weigand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Schlundt· 2 shared L. Oberstrass· 2 shared E. Yazgan· 1 shared F. McNicoll· 1 shared J. von Ehr· 1 shared J.-N. Tants· 1 shared K. Zarnack· 1 shared L. I. Schnaubelt· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

A. Schlundt

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Author profile →

2 papers

Recent·Most cited

Structure and RNA-binding of the helically extended Roquin CCCH-type zinc finger

J.-N. Tants, L. Oberstrass, J. E. Weigand, A. Schlundt

This study determines the structure of the Roquin ZnF domain and shows it binds AU-rich elements, revealing how Roquin integrates RNA shape and sequence specificity through its ROQ-ZnF tandem.

bioRxiv · Mar 1, 2024Biochemistry

Arid5a uses disordered extensions of its core ARID domain for distinct DNA- and RNA-recognition and gene regulation

J. von Ehr, L. Oberstrass, E. Yazgan, L. I. Schnaubelt, N. Bluemel, F. McNicoll, J. E. Weigand, K. Zarnack, M. Mueller-McNicoll, S. M. Korn, A. Schlundt

This study defines Arid5a's DNA and RNA-binding preferences using biochemical and high-throughput methods, showing that disordered regions modulate its nucleic acid interactions and gene regulation.

bioRxiv · Feb 29, 2024Biochemistry