Structure and RNA-binding of the helically extended Roquin CCCH-type zinc finger
J.-N. Tants, L. Oberstrass, J. E. Weigand, A. Schlundt
This study determines the structure of the Roquin ZnF domain and shows it binds AU-rich elements, revealing how Roquin integrates RNA shape and sequence specificity through its ROQ-ZnF tandem.
bioRxiv · Mar 1, 2024Biochemistry