Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages
J. E. Zarrow, A.-M. Alli-Oluwafuyi, C. M. Youwakim, K. Kim, A. N. Jenkins, I. C. Suero, M. R. Jones, Z. Mashhadi, K. P. Mackie, A. G. Waterson, A. C. Doran, G. A. Sulikowski, S. S. Davies
This study identifies small molecule activators of NAPE-PLD that enhance efferocytosis by macrophages, suggesting their potential therapeutic use in cardiometabolic diseases.
bioRxiv · Jan 25, 2023Biochemistry