J. F. Allard

Intrinsic disorder in the T cell receptor creates cooperativity and controls ZAP70 binding

This paper uses simulations to show how intrinsic disorder in T cell receptor chains leads to nonlinear signaling through entropy changes, affecting ZAP70 binding and cooperativity.

Roles of motor on-rate and cargo mobility in intracellular transport

This study measures the single motor on rate for kinesin-1 cargo binding to microtubules, finding a higher rate than previous estimates due to direct measurement and improved theoretical modeling.