Development of a physiological insulin resistance model in human stem cell-derived adipocytes
M. Friesen, A. S. Khalil, M. I. Barrasa, J. F. Jeppesen, D. Mooney, R. Jaenisch
This paper develops a protocol to generate human pluripotent stem cell-derived adipocytes that respond to physiological insulin levels and model insulin resistance in diabetes.
bioRxiv · Feb 22, 2022Cell Biology