Functional interplay between SWI/SNF complexes underlies BRD9 dependency in SMARCB1-mutant cancers
R. J. Mobley, J. A. Myers, K. M. Wills, H. A. Malone, T. I. Manzano, J. F. Partridge, C. W. M. Roberts
The paper investigates the functional interactions between SWI/SNF chromatin remodeling complexes, showing that SMARCB1 loss affects BRD9 binding and contributes to oncogenesis in SMARCB1-mutant cancers.
bioRxiv · Aug 7, 2022 · PreprintCancer Biology