Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells
J. G. Dierolf, H. L. M. Hunter, A. J. Watson, D. H. Betts
This study modulates PKM1/2 levels in mouse pluripotent stem cells using morpholinos, showing altered metabolic and pluripotent states, particularly affecting the formative state transition.
bioRxiv · Nov 23, 2021Cell Biology