Author

A. J. Watson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. H. Betts· 2 shared J. G. Dierolf· 2 shared C. Alcon-Giner· 1 shared C. S. Evans· 1 shared D. T. Huynh· 1 shared E. J. Soderblom· 1 shared F. Bernuzzi· 1 shared G. Le Gall· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

D. H. Betts

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations

D. T. Huynh, J. Hu, J. R. Schneider, K. N. Tsolova, E. J. Soderblom, A. J. Watson, J.-T. A. Chi, C. S. Evans, M. Boyce

This study shows that O-GlcNAcylation regulates NF-L assembly and function, and CMT mutations disrupt this process, linking glycosylation defects to neurodegeneration.

bioRxiv · Feb 22, 2023Cell Biology

Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells

J. G. Dierolf, H. L. M. Hunter, A. J. Watson, D. H. Betts

This study modulates PKM1/2 levels in mouse pluripotent stem cells using morpholinos, showing altered metabolic and pluripotent states, particularly affecting the formative state transition.

bioRxiv · Nov 23, 2021Cell Biology

Differential localization patterns of pyruvate kinase isoforms in murine naïve, formative and primed pluripotent states

J. G. Dierolf, A. J. Watson, D. H. Betts

This study examines the differential subnuclear localization of PKM1 and PKM2 in mouse pluripotent states and validates methods for assessing protein colocalization.

bioRxiv · Apr 12, 2020Cell Biology

The early life microbiota protects neonatal mice from pathological small intestinal epithelial cell shedding

K. R. Hughes, Z. Schofield, M. J. Dalby, S. Caim, L. Chalklen, F. Bernuzzi, C. Alcon-Giner, G. Le Gall, A. J. Watson, L. J. Hall

This study shows that early life gut microbiota in mice prevents pathological small intestinal epithelial cell shedding, with antibiotic treatment reversing this protection.

bioRxiv · Oct 2, 2019Microbiology