Direct Nucleosome Binding of Borealin Secures Chromosome Association and Function of the Chromosomal Passenger complex
M. A. Abad, J. G. Ruppert, L. Buzuk, M. Wear, J. Zou, K. M. Webb, D. A. Kelly, P. Voigt, J. Rappsilber, W. C. Earnshaw, A. A. Jeyaprakash
This study identifies Borealin as the key mediator of Chromosomal Passenger Complex (CPC) chromosome association through direct nucleosome binding, revealing its critical role in chromosome segregation.
bioRxiv · Apr 26, 2019Cell Biology