Temporal Analysis of T-Cell Receptor-Imposed Forces via Quantitative Single Molecule FRET Measurements
J. Göhring, F. Kellner, L. Schrangl, R. Platzer, E. Klotzsch, H. Stockinger, J. B. Huppa, G. Schuetz
The paper measures T-cell receptor forces using single molecule FRET, finding a 5 pN force peak during T-cell activation on gel-phase SLBs.
Nature Communications · May 4, 2021Peer-reviewedBiophysics